Canada Research Chair in Metabolism in Human Stem Cells and Cancer Development
Assistant Professor, Department of Biochemistry and Biomedical Sciences & Department of Medicine
Location: MDCL 5022
"We all have family and friends that are suffering from metabolic diseases, such as obesity, and we see the social stigma that comes with it. However, society doesn’t understand that obesity is a disease and should not be solely attributed to lifestyle choices. Therefore, my research is trying to understand how obesity develops, what causes downstream complications, and how we can treat these effectively, while simultaneously educating the public about the disease."
Dr. Eva Szabo’s research program is focused on metabolic diseases. She is particularly interested in obesity and type 2 diabetes, and their downstream complications, neuropathy and cardiovascular disease.
Through the use of reprogramming strategies, the Szabo lab is using patient-derived stem cells to create novel models of these diseases in vitro. These models allow the lab to determine both how resident stem cell populations are affected by metabolic diseases, and also how they can be harnessed towards the development of novel therapeutics.
The ultimate goal is to develop novel models of these diseases to address the gap in knowledge about how these conditions develop and how they can be treated in a targeted manner.
Understanding the role of genetics in early onset cardiovascular artery disease development to provide new therapeutic and risk management avenues.
Developing targeted, patient-specific treatment strategies for neuropathy induced by obesity and Type 2 Diabetes.
Developing novel and effective treatment strategies for obesity.
Nature. 2010 Nov 25;468(7323):521-6.