Pre-clinical modelling is a critical transitional step in determining whether research findings are physiologically relevant. This step is essential for bringing in vitro findings to testing in human clinical trials. Our approach is to continuously innovate new models of disease to begin testing early in the research process, ultimately ensuring translational capacity.
To identify novel therapeutics that can target the bone marrow environment to destroy and prevent leukemia. By better understanding the optimal bone marrow conditions needed to support healthy blood stem cells, this study also has the potential to improve stem cell transplantation therapies.