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Cancer

Cancer is the leading cause of death in Canada. Two cancers we are particularly focused on are Acute Myeloid Leukemia (AML), a lethal cancer of the blood system, and Glioblastoma Multiforme (GBM), an aggressive brain cancer with an unsettlingly high recurrence rate. Our approach is to further our understanding of the cells implicated in these diseases to ultimately determine how they can be predicted, managed and eliminated.

Principal Investigators

Mick Bhatia

Mick Bhatia

Director and Senior Scientist

Brad Doble

Brad Doble

Principal Investigator

Jon Draper

Jon Draper

Principal Investigator

Kristin Hope

Kristin Hope

Principal Investigator

Sheila Singh

Sheila Singh

Principal Investigator

Related Projects

To identify novel therapeutics that can target the bone marrow environment to destroy and prevent leukemia. By better understanding the optimal bone marrow conditions needed to support healthy blood stem cells, this study also has the potential to improve stem cell transplantation therapies.

The combination of standard of care chemotherapy, coupled with novel drugs discovered by our group, is hoped to prevent cancer relapse.

Demonstrating the ability of the Wnt pathway to suppress tumour progression in childhood medulloblastoma, thus establishing activated Wnt signaling as a novel treatment paradigm.

Related News

Canadian Cancer Society's Daffodil Campaign and CHCH's Interview with Mick Bhatia

Canadian Cancer Society's Daffodil Campaign and CHCH's Interview with Mick Bhatia

To kick off Daffodil Month, CHCH News visited the SCC-RI to learn about research and how it is impacting patient care in Hamilton. We reflect back on that interview. [...]

Darlene Lane

Darlene Lane | Tuesday, April 10, 2018

StemCellTalks 2018 at McMaster University Brings Discussions of Making Sci-Fi Medicine a Modern Reality

StemCellTalks 2018 at McMaster University Brings Discussions of Making Sci-Fi Medicine a Modern Reality

StemCellTalks coordinator, Damian Tran, recounts the inspiring moments of the symposium, which aimed to engage senior high school students with introductory stem cell biology. [...]

Damian Tran

Damian Tran | Thursday, March 29, 2018

Spoiling the soil for leukemia favours normal blood cells

Spoiling the soil for leukemia favours normal blood cells

Promoting fat cells in the bone marrow inhibits leukemic cells but promotes normal blood generation [...]

Tony Collins

Tony Collins | Monday, October 16, 2017